简要描述:37215压力测试仪是经典的7200paw压力测试仪的升级产品,自1965年使用以来,该测试仪在多个学术和工业实验室为镇痛药物的开发和研究做出了贡献
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37215压力测试仪是经典的7200 paw压力测试仪的升级产品,自1965年使用以来,该测试仪在多个学术和工业实验室为镇痛药物的开发和研究做出了贡献。
压痛仪的主要特点:
· 提供三种测试量程:250g,500g,750g
· 简单可靠:无需校准!
· 标准为砝码测试型号,可根据需要选择数字显示型号;
· 提供小鼠专用型号,测量更准确;
· 1960年代以来的经典方法:发表论文数百篇!
型号:37215型
· 爪子放置在带有圆形的锥形推动器下方的小底座上;
· 操作人员按下踏板开关,压力由小到大施加到动物的爪子上;
· 力以恒定速率增加,使得测试具备很好的可重复性;
· 动物感受到疼痛时会产生躲避反应;
· 松开踏板开关,压力立即停止;
· 在以10g为步进单位施加力;
· 采用低压同步电机,符合CE规则;
· 根据需要,可选择小鼠专用的型号;
· 数显型号更容易记录数据和读取数据;
· 传统款式和数显款式采用箱体的测试结构,测量数据一致;
· 数字显示器采用模块化设计,可以对传统款式进行升级;
37215型压痛仪的主要规格
· 电源:115或230V,50/60Hz
· 功率:15W
· 操控方式:踏板开关
· 尺寸:40 x 16 x 14cm
· 重量:2.1Kg
型号和测试量程
· 37215,大鼠小鼠通用型:250g,500g,750g
· 37216,小鼠型号:125g,250g,375g
压力模块
参考文献:
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safety profile compared to strong opioids." Acta pharmaceutica Sinica. B vol. 13,1 (2023): 82-99. doi:10.1016/j.apsb.2022.09.018
7.Mousa, Shaaban A et al. “Superior control of inflammatory pain by corticotropin-releasing factor receptor 1 via opioid peptides in distinct pain-relevant brain
areas." Journal of neuroinflammation vol. 19,1 148. 15 Jun. 2022, doi:10.1186/s12974-022-02498-8
8.Zhou, Danli et al. “Inhibition of apoptosis signal-regulating kinase by paeoniflorin attenuates neuroinflammation and ameliorates neuropathic pain." Journal of
neuroinflammation vol. 16,1 83. 11 Apr. 2019, doi:10.1186/s12974-019-1476-6
9.Wang, Wenying et al. “Exchange factor directly activated by cAMP-PKCε signalling mediates chronic morphine-induced expression of purine P2X3 receptor in rat
dorsal root ganglia." British journal of pharmacology vol. 175,10 (2018): 1760-1769. doi:10.1111/bph.14191
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